Effect of purified omega-3 fatty acids on reducing left ventricular remodeling after acute myocardial infarction (OMEGA-REMODEL study): a double-blind randomized clinical trial)
نویسندگان
چکیده
Effect of purified omega-3 fatty acids on reducing left ventricular remodeling after acute myocardial infarction (OMEGA-REMODEL study): a double-blind randomized clinical trial) Bobby Heydari, Siddique A Abbasi, Ravi Shah, Shuaib Abdullah, Jiazuo Feng, William Harris, Joe McConnell, Evan Appelbaum, Udo Hoffmann, Michael Steigner, Ron Blankstein, Elliott A Antman, Michael Jerosch-Herold, Raymond Y Kwong
منابع مشابه
Epidemiology and Prevention OMEGA, a Randomized, Placebo-Controlled Trial to Test the Effect of Highly Purified Omega-3 Fatty Acids on Top of Modern Guideline-Adjusted Therapy After Myocardial Infarction
Background—There is no randomized, double-blind trial testing the prognostic effect of highly purified omega-3 fatty acids in addition to current guideline-adjusted treatment of acute myocardial infarction. Methods and Results—OMEGA is a randomized, placebo-controlled, double-blind, multicenter trial testing the effects of omega-3-acid ethyl esters-90 (1 g/d for 1 year) on the rate of sudden ca...
متن کاملOMEGA, a randomized, placebo-controlled trial to test the effect of highly purified omega-3 fatty acids on top of modern guideline-adjusted therapy after myocardial infarction.
BACKGROUND There is no randomized, double-blind trial testing the prognostic effect of highly purified omega-3 fatty acids in addition to current guideline-adjusted treatment of acute myocardial infarction. METHODS AND RESULTS OMEGA is a randomized, placebo-controlled, double-blind, multicenter trial testing the effects of omega-3-acid ethyl esters-90 (1 g/d for 1 year) on the rate of sudden ...
متن کاملLetter by Alter and Rupp regarding article, "OMEGA, a randomized, placebo-controlled trial to test the effect of highly purified omega-3 fatty acids on top of modern guideline-adjusted therapy after myocardial infarction".
In the OMEGA study on patients after myocardial infarction, 1 the anticipated statistical power of 80% was not reached, which was attributed to the low incidence of sudden cardiac death in patients receiving current guideline-adjusted medical treatment. To detect an improvement of clinical outcome by omega-3 fatty acids, it is considered important to focus on patients with poor heart function. ...
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Background: Cardiovascular disease (CVD) is the leading cause of mortality worldwide. Omega-3 fatty acids have been shown to have both anti-atherogenic and anti-inflammatory effects through inducing the expression and production of adipokines. Adipokines such as apelin, have been observed to play a protective role in the incidence and progression of CVD. The aim of this study was to assess the ...
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BACKGROUND Fish is the natural dietary source of vitamin D. Reports on the influence of purified omega-3 fatty acids on its uptake are scarce. OBJECTIVES We investigated the impact of a purified high-dose omega-3 compound compared to corn oil on 25-hydroxyvitamin D [25(OH)D] levels following an acute myocardial infarction. METHODS 228 patients were randomized 1:1 to receive a daily dose of ...
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